Ketamine is being increasingly researched as a treatment for severe depression, as well as for other physical and mental disorders. Here are links to some of the ketamine research that has been done:


Antidepressant Efficacy of Ketamine in Treatment-Resistant Major Depression: A Two-Site Randomized Controlled Trial
American Journal of Psychiatry, 2013

Rapid and Longer-Term Antidepressant Effects of Repeated Ketamine Infusions in Treatment-Resistant Major Depression
Society of Biological Psychiatry, 2012

Synaptic Dysfunction in Depression: Potential Therapeutic Targets
Science Magazine, 2012

Safety and Efficacy of Repeated-Dose Intravenous Ketamine for Treatment-Resistant Depression
Society of Biological Psychiatry, 2010

Glutamate NMDA receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure
Society of Biological Psychiatry, 2010

Maintenance Ketamine Treatment Produces Long-term Recovery from Depression
Primary Psychiatry, 2010